Oncology

Chronic Lymphocytic Leukemia

Expert Roundtables Podcast: Challenges in the Diagnosis and Management of Accelerated Chronic Lymphocytic Leukemia or Richter’s Transformation

expert roundtables by Ian W. Flinn, MD, PhD; Sameer A. Parikh, MBBS; Kerry A. Rogers, MD

The diagnosis of accelerated chronic lymphocytic leukemia (CLL) and Richter’s transformation (RT) presents challenges. An accurate diagnosis can be difficult to establish and is urgent because accelerated CLL and RT are aggressive and require prompt treatment. Our expert panel reviews current options for diagnosis and management in this Expert Roundtables discussion.

References

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Levy Yurkovski I, Tadmor T. Accelerated chronic lymphocytic leukemia and Richter transformation in the era of novel agents. Acta Haematol. 2024;147(1):73-83. doi:10.1159/000533664

Odetola O, Ma S. Relapsed/refractory chronic lymphocytic leukemia (CLL). Curr Hematol Malig Rep. 2023;18(5):130-143. doi:10.1007/s11899-023-00700-z

Ryan CE, Davids MS. Practical management of Richter transformation in 2023 and beyond. Am Soc Clin Oncol Educ Book. 2023;43:e390804. doi:10.1200/EDBK_390804

Thompson PA, Siddiqi T. Treatment of Richter’s syndrome. Hematology Am Soc Hematol Educ Program. 2022;2022(1):329-336. doi:10.1182/hematology.2022000345